You’ll need a notarized letter from the lien holder giving you permission to take the vehicle into Mexico (it’s so much easier if you own the vehicle outright).  You should plan to stay on the toll roads – have your pesos ready – these are the safest roads to drive.  Don’t opt to make this a sight seeing trip – unless you’ve done it several times before – you are moving all your personal belongings and that is stressful enough.  You need to itemize a list of your belongings – in case they ask you for it at the border.  You’ll need to know the address of where you are planning to unload.  Your vehicle will need an import permit plus you’ll pay an immigration fee.  Carrying a gun across the border can get you a $25,000 fine and up to 25 years in jail.  Don’t drive at night.  Not all hotels allow pets.  Nice to have a locking pin for your license plate, just in case.  Have a map in case you don’t have WiFi service.  You may be denied entry if you’ve had a DUI in the last 10 years.

In other words, be smart about it.  Do your research.  Go with your gut on choosing the safest place to stay.  Have a backup plan.